Pre-Alex I've ran through 5 months of mails, which amounted to ~5k mails, and sorted them out (there was already label Waiting done for me).
Post-Alex, in 2 months of mails the sample size was ~2k mails.
Number of e-mail addresses contacted within those 7 month period is ~70.
So you send ~50 mail every (working) day?
Could your sheer volume skew the result?
(as in: spam people and they start to ignore you, put someone on CC and they have reason to believe it's worth reading?)